Research library: browse by date
The Research Library categorizes and alerts you to recent neuroscience- and genomics-related research in journals from the Nature family and from other publishers. Primary research and review articles are included, as are News and Views.
July 2006
Kinase Suppressor of Ras1 Compartmentalizes Hippocampal Signal Transduction and Subserves Synaptic Plasticity and Memory Formation
S Shalin, C Hernandez, M Dougherty, D Morrison & J Sweatt
Neuron 50
(1 June 2006); doi:10.1016/j.neuron.2006.04.029The Tip-Link Antigen, a Protein Associated with the Transduction Complex of Sensory Hair Cells, Is Protocadherin-15
Z. M. Ahmed
Journal of Neuroscience 26
(28 June 2006); doi:10.1523/JNEUROSCI.1163-06.2006The Muscle Protein Dok-7 Is Essential for Neuromuscular Synaptogenesis
K. Okada
Science 312
(23 June 2006); doi:10.1126/science.1127142Phototransduction in a Transgenic Mouse Model of Nougaret Night Blindness
M. Moussaif
Journal of Neuroscience 26
(21 June 2006); doi:10.1523/JNEUROSCI.1322-06.2006Kiss1 Neurons in the Forebrain as Central Processors for Generating the Preovulatory Luteinizing Hormone Surge
J. T. Smith
Journal of Neuroscience 26
(21 June 2006); doi:10.1523/JNEUROSCI.1618-06.2006Opposing Crosstalk between Leptin and Glucocorticoids Rapidly Modulates Synaptic Excitation via Endocannabinoid Release
R. Malcher-lopes
Journal of Neuroscience 26
(14 June 2006); doi:10.1523/JNEUROSCI.5126-05.2006FGF as a Target-Derived Chemoattractant for Developing Motor Axons Genetically Programmed by the LIM Code
R Shirasaki, J Lewcock, K Lettieri & S Pfaff
Neuron 50
(15 June 2006); doi:10.1016/j.neuron.2006.04.030Essential Role of the Apoptotic Cell Engulfment Genes draper and ced-6 in Programmed Axon Pruning during Drosophila Metamorphosis
T Awasaki, R Tatsumi, K Takahashi, K Arai, Y Nakanishi, R Ueda & K Ito
Neuron 50
(15 June 2006); doi:10.1016/j.neuron.2006.04.027The Drosophila Cell Corpse Engulfment Receptor Draper Mediates Glial Clearance of Severed Axons
J Macdonald, M Beach, E Porpiglia, A Sheehan, R Watts & M Freeman
Neuron 50
(15 June 2006); doi:10.1016/j.neuron.2006.04.028Wlds Protection Distinguishes Axon Degeneration following Injury from Naturally Occurring Developmental Pruning
E Hoopfer, T Mclaughlin, R Watts, O Schuldiner, D Oleary & L Luo
Neuron 50
(15 June 2006); doi:10.1016/j.neuron.2006.05.013Activity-Dependent Dendritic Arborization Mediated by CaM-Kinase I Activation and Enhanced CREB-Dependent Transcription of Wnt-2
G Wayman, S Impey, D Marks, T Saneyoshi, W Grant, V Derkach & T Soderling
Neuron 50
(15 June 2006); doi:10.1016/j.neuron.2006.05.008Hierarchical Control of Dopamine Neuron-Firing Patterns by Nicotinic Receptors
M Mameliengvall, A Evrard, S Pons, U Maskos, T Svensson, J Changeux & P Faure
Neuron 50
(15 June 2006); doi:10.1016/j.neuron.2006.05.007The Myotomal diwanka (lh3) Glycosyltransferase and Type XVIII Collagen Are Critical for Motor Growth Cone Migration
V Schneider & M Granato
Neuron 50
(1 June 2006); doi:10.1016/j.neuron.2006.04.024Short hairpin RNA–expressing bacteria elicit RNA interference in mammals
Shuanglin Xiang, Johannes Fruehauf & Chiang J Li
Nature Biotechnology
(14 May 2006); doi:10.1038/nbt1211A Topoisomerase II -Mediated dsDNA Break Required for Regulated Transcription
B.-G. Ju
Science 312
(23 June 2006); doi:10.1126/science.1127196JETLAG Resets the Drosophila Circadian Clock by Promoting Light-Induced Degradation of TIMELESS
K. Koh
Science 312
(23 June 2006); doi:10.1126/science.1124951Impaired Nociception and Inflammatory Pain Sensation in Mice Lacking the Prokineticin Receptor PKR1: Focus on Interaction between PKR1 and the Capsaicin Receptor TRPV1 in Pain Behavior
L. Negri
Journal of Neuroscience 26
(21 June 2006); doi:10.1523/JNEUROSCI.5403-05.2006Cardiac glycosides provide neuroprotection against ischemic stroke: Discovery by a brain slice-based compound screening platform
J. K. T. Wang
Proceedings of the National Academy of Sciences 103
(5 July 2006); doi:10.1073/pnas.0600930103Amygdala BDNF signaling is required for consolidation but not encoding of extinction
Jasmeer P Chhatwal, Lisa Stanek-rattiner, Michael Davis & Kerry J Ressler
Nature Neuroscience 9 870 - 872
(18 June 2006); doi:10.1038/nn1718Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes
K. Kamprath
Journal of Neuroscience 26
(21 June 2006); doi:10.1523/JNEUROSCI.0153-06.2006Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy
Sedigheh Delmaghani, Francisco J Del castillo, Vincent Michel, Michel Leibovici, Asadollah Aghaie, Uri Ron, Lut Van laer, Nir Ben-tal, Guy Van camp, Dominique Weil, Francina Langa, Mark Lathrop, Paul Avan & Christine Petit
Nature Genetics 38 770 - 778
(25 June 2006); doi:10.1038/ng1829Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease
Mark I Rees, Kirsten Harvey, Brian R Pearce, Seo-Kyung Chung, Ian C Duguid, Philip Thomas, Sarah Beatty, Gail E Graham, Linlea Armstrong, Rita Shiang, Kim J Abbott, Sameer M Zuberi, John B P Stephenson, Michael J Owen, Marina A J Tijssen, Arn M J M Van den maagdenberg, Trevor G Smart, Stéphane Supplisson & Robert J Harvey
Nature Genetics 38 801 - 806
(4 June 2006); doi:10.1038/ng1814AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc
Vikram R Rao, Sean A Pintchovski, Jeannie Chin, Carol L Peebles, Siddhartha Mitra & Steven Finkbeiner
Nature Neuroscience 9 887 - 895
(28 May 2006); doi:10.1038/nn1708Daniel E Zak, Haiping Hao, Rajanikanth Vadigepalli, Gregory M Miller, Babatunde A Ogunnaike & James S Schwaber
Genome Biology 7
(1 January 2006); doi:10.1186/gb-2006-7-6-r48Jeremy C Simpson & Rainer Pepperkok
Genome Biology 7
(1 January 2006); doi:10.1186/gb-2006-7-6-213Physical map-assisted whole-genome shotgun sequence assemblies
R. L. Warren
Genome Research 16
(1 June 2006); doi:10.1101/gr.5090606The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila
B. Bello
Development 133
(15 July 2006); doi:10.1242/dev.02429Adenoviral-Mediated Modulation of Sim1 Expression in the Paraventricular Nucleus Affects Food Intake
C. Yang
Journal of Neuroscience 26
(28 June 2006); doi:10.1523/JNEUROSCI.0672-06.2006PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron
Neil V Morgan, Shawn K Westaway, Jenny E V Morton, Allison Gregory, Paul Gissen, Scott Sonek, Hakan Cangul, Jason Coryell, Natalie Canham, Nardo Nardocci, Giovanna Zorzi, Shanaz Pasha, Diana Rodriguez, Isabelle Desguerre, Amar Mubaidin, Enrico Bertini, Richard C Trembath, Alessandro Simonati, Carolyn Schanen, Colin A Johnson, Barbara Levinson, C Geoffrey Woods, Beth Wilmot, Patricia Kramer, Jane Gitschier, Eamonn R Maher & Susan J Hayflick
Nature Genetics 38 752 - 754
(18 June 2006); doi:10.1038/ng1826Notch signalling regulates stem cell numbers in vitro and in vivo
Andreas Androutsellis-theotokis, Ronen R. Leker, Frank Soldner, Daniel J. Hoeppner, Rea Ravin, Steve W. Poser, Maria A. Rueger, Soo-Kyung Bae, Raja Kittappa & Ronald D. G. Mckay
Nature 442 823 - 826
(25 June 2006); doi:10.1038/nature04940Effective gene therapy in an authentic model of Tay-Sachs-related diseases
M. B. Cachon-gonzalez
Proceedings of the National Academy of Sciences 103
(5 July 2006); doi:10.1073/pnas.0603765103JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport
Gerardo Morfini, Gustavo Pigino, Györgyi Szebenyi, Yimei You, Sarah Pollema & Scott T Brady
Nature Neuroscience 9 907 - 916
(4 June 2006); doi:10.1038/nn1717From the Cover: Nonvisual light responses in the Rpe65 knockout mouse: Rod loss restores sensitivity to the melanopsin system
S. E. Doyle
Proceedings of the National Academy of Sciences 103
(5 July 2006); doi:10.1073/pnas.0600934103RNAi-mediated silencing of estrogen receptor in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors
S. Musatov
Proceedings of the National Academy of Sciences 103
(5 July 2006); doi:10.1073/pnas.0603045103Interaction of two hereditary spastic paraplegia gene products, spastin and atlastin, suggests a common pathway for axonal maintenance
K. Evans
Proceedings of the National Academy of Sciences 103
(11 July 2006); doi:10.1073/pnas.0510863103Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins
S. Moriguchi
Proceedings of the National Academy of Sciences 103
(11 July 2006); doi:10.1073/pnas.0509863103A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor
F. Jeanneteau
Proceedings of the National Academy of Sciences 103
(11 July 2006); doi:10.1073/pnas.0508189103Altered Balance of Glutamatergic/GABAergic Synaptic Input and Associated Changes in Dendrite Morphology after BDNF Expression in BDNF-Deficient Hippocampal Neurons
B. Singh
Journal of Neuroscience 26
(5 July 2006); doi:10.1523/JNEUROSCI.5474-05.2006Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript
A. Gupta, J. J. Gartner, P. Sethupathy, A. G. Hatzigeorgiou & N. W. Fraser
Nature 442 82 - 85
(31 May 2006); doi:10.1038/nature04836A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
Joanna Wysocka, Tomek Swigut, Hua Xiao, Thomas A. Milne, So Yeon Kwon, Joe Landry, Monika Kauer, Alan J. Tackett, Brian T. Chait, Paul Badenhorst, Carl Wu & C. David Allis
Nature 442 86 - 90
(21 May 2006); doi:10.1038/nature04815Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF
Haitao Li, Serge Ilin, Wooikoon Wang, Elizabeth M. Duncan, Joanna Wysocka, C. David Allis & Dinshaw J. Patel
Nature 442 91 - 95
(21 May 2006); doi:10.1038/nature04802ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression
Xiaobing Shi, Tao Hong, Kay L. Walter, Mark Ewalt, Eriko Michishita, Tiffany Hung, Dylan Carney, Pedro Peña, Fei Lan, Mohan R. Kaadige, Nicolas Lacoste, Christelle Cayrou, Foteini Davrazou, Anjanabha Saha, Bradley R. Cairns, Donald E. Ayer, Tatiana G. Kutateladze, Yang Shi, Jacques Côté, Katrin F. Chua & Or Gozani
Nature 442 96 - 99
(21 May 2006); doi:10.1038/nature04835Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2
Pedro V. Peña, Foteini Davrazou, Xiaobing Shi, Kay L. Walter, Vladislav V. Verkhusha, Or Gozani, Rui Zhao & Tatiana G. Kutateladze
Nature 442 100 - 103
(21 May 2006); doi:10.1038/nature04814The amyloid code
Standfirst
Is there a conspiracy afoot to keep one theory dominant in Alzheimer disease research? Maybe not, but as Apoorva Mandavilli discovers, it may still be high time for new ideas.
Apoorva Mandavilli
Nature Medicine 12 747 - 751
(28 June 2006); doi:10.1038/nm0706-747Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
Min-Seon Kim, Youngmi K Pak, Pil-Geum Jang, Cherl Namkoong, Yon-Sik Choi, Jong-Chul Won, Kyung-Sup Kim, Seung-Whan Kim, Hyo-Soo Kim, Joong-Yeol Park, Young-Bum Kim & Ki-Up Lee
Nature Neuroscience 9 901 - 906
(18 June 2006); doi:10.1038/nn1731In Vivo Restoration of Physiological Levels of Truncated TrkB.T1 Receptor Rescues Neuronal Cell Death in a Trisomic Mouse Model
S Dorsey, C Renn, L Carimtodd, C Barrick, L Bambrick, B Krueger, C Ward & L Tessarollo
Neuron 51
(6 July 2006); doi:10.1016/j.neuron.2006.06.009Nedd4-WW Domain-Binding Protein 5 (Ndfip1) Is Associated with Neuronal Survival after Acute Cortical Brain Injury
Q. Sang
Journal of Neuroscience 26
(5 July 2006); doi:10.1523/JNEUROSCI.1398-06.2006p120 Catenin Regulates Dendritic Spine and Synapse Development through Rho-Family GTPases and Cadherins
L Elia, M Yamamoto, K Zang & L Reichardt
Neuron 51
(6 July 2006); doi:10.1016/j.neuron.2006.05.018Highwire Restrains Synaptic Growth by Attenuating a MAP Kinase Signal
C Collins, Y Wairkar, S Johnson & A Diantonio
Neuron 51
(6 July 2006); doi:10.1016/j.neuron.2006.05.026Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein
C. Priller
Journal of Neuroscience 26
(5 July 2006); doi:10.1523/JNEUROSCI.1450-06.2006Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration
A Salehi, J Delcroix, P Belichenko, K Zhan, C Wu, J Valletta, R Takimotokimura, A Kleschevnikov, K Sambamurti & P Chung
Neuron 51
(6 July 2006); doi:10.1016/j.neuron.2006.05.022Alternative N-Terminal Domains of PSD-95 and SAP97 Govern Activity-Dependent Regulation of Synaptic AMPA Receptor Function
O Schluter, W Xu & R Malenka
Neuron 51
(6 July 2006); doi:10.1016/j.neuron.2006.05.016DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays
Gregory E Crawford, Sean Davis, Peter C Scacheri, Gabriel Renaud, Mohamad J Halawi, Michael R Erdos, Roland Green, Paul S Meltzer, Tyra G Wolfsberg & Francis S Collins
Nature Methods 3 503 - 509
(21 June 2006); doi:10.1038/nmeth888Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays
Peter J Sabo, Michael S Kuehn, Robert Thurman, Brett E Johnson, Ericka M Johnson, Hua Cao, Man Yu, Elizabeth Rosenzweig, Jeff Goldy, Andrew Haydock, Molly Weaver, Anthony Shafer, Kristin Lee, Fidencio Neri, Richard Humbert, Michael A Singer, Todd A Richmond, Michael O Dorschner, Michael Mcarthur, Michael Hawrylycz, Roland D Green, Patrick A Navas, William S Noble & John A Stamatoyannopoulos
Nature Methods 3 511 - 518
(21 June 2006); doi:10.1038/nmeth890Nogo-A–specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates
Patrick Freund, Eric Schmidlin, Thierry Wannier, Jocelyne Bloch, Anis Mir, Martin E Schwab & Eric M Rouiller
Nature Medicine 12 790 - 792
(2 July 2006); doi:10.1038/nm1436A transgenic triple scores a home run
Standfirst
Plaques and tangles populate the brains of people with Alzheimer disease. A mouse model that contains both of these lesions is providing insights into how the proteins that make up these hallmarks of the disease interact.
Greg Cole
Nature Medicine 12 762 - 763
doi:10.1038/nm0706-762An Early Role for Wnt Signaling in Specifying Neural Patterns of Cdx and Hox Gene Expression and Motor Neuron Subtype Identity
Ulrika Nordström, Esther Maier, Thomas M. Jessell & Thomas Edlund
PLoS Biology 4
(1 January 2006); doi:10.1371/journal.pbio.0040252Modeling Chromosomes in Mouse to Explore the Function of Genes, Genomic Disorders, and Chromosomal Organization
Véronique Brault, Patricia Pereira, Arnaud Duchon & Yann Hérault
PLoS Genetics 2
(1 January 2006); doi:10.1371/journal.pgen.0020086