October 2006

• Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations

  H Tu, O Nelson, A Bezprozvanny, Z Wang, S Lee, Y Hao, L Serneels, B Destrooper, G Yu & I Bezprozvanny
  Cell 126
  (8 September 2006); doi:10.1016/j.cell.2006.06.059

  Abstract

• The Prototoxin lynx1 Acts on Nicotinic Acetylcholine Receptors to Balance Neuronal Activity and Survival In Vivo

  J Miwa, T Stevens, S King, B Caldarone, I Ibaneztallon, C Xiao, R Fitzsimonds, C Pavlides, H Lester & M Picciotto
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.07.025

  Abstract

• The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance

  Kazuo Emoto, Jay Z. Parrish, Lily Yeh Jan & Yuh-Nung Jan
  Nature 443 210 - 213
  (13 August 2006); doi:10.1038/nature05090

  Abstract

• Pregnane X receptor (PXR) activation: A mechanism for neuroprotection in a mouse model of Niemann-Pick C disease

  S. J. Langmade
  Proceedings of the National Academy of Sciences 103
  (12 September 2006); doi:10.1073/pnas.0606218103

  Abstract

• Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6

  M. Poet
  Proceedings of the National Academy of Sciences 103
  (12 September 2006); doi:10.1073/pnas.0606137103

  Abstract

• Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials

  A. Ferri
  Proceedings of the National Academy of Sciences 103
  (12 September 2006); doi:10.1073/pnas.0605814103

  Abstract

• Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus

  R. Yoshimoto
  Proceedings of the National Academy of Sciences 103
  (12 September 2006); doi:10.1073/pnas.0506104103

  Abstract

•  -Synuclein Overexpression Increases Cytosolic Catecholamine Concentration

  E. V. Mosharov
  Journal of Neuroscience 26
  (6 September 2006); doi:10.1523/JNEUROSCI.0519-06.2006

  Abstract

• DARPP-32 Involvement in the Photic Pathway of the Circadian System

  L. Yan
  Journal of Neuroscience 26
  (13 September 2006); doi:10.1523/JNEUROSCI.2538-06.2006

  Abstract

• Knockdown of Nav 1.6a Na+ channels affects zebrafish motoneuron development

  R. H. Pineda
  Development 133
  (1 October 2006); doi:10.1242/dev.02559

  Abstract

• Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

  Frank H Yu, Massimo Mantegazza, Ruth E Westenbroek, Carol A Robbins, Franck Kalume, Kimberly A Burton, William J Spain, G Stanley Mcknight, Todd Scheuer & William A Catterall
  Nature Neuroscience 9 1142 - 1149
  (20 August 2006); doi:10.1038/nn1754

  Abstract

• RGS2 Determines Short-Term Synaptic Plasticity in Hippocampal Neurons by Regulating Gi/o- Mediated Inhibition of Presynaptic Ca2+ Channels

  J Han, M Mark, X Li, M Xie, S Waka, J Rettig & S Herlitze
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.07.012

  Abstract

• Mice Deficient for the Vesicular Acetylcholine Transporter Are Myasthenic and Have Deficits in Object and Social Recognition

  V Prado, C Martinssilva, B Decastro, R Lima, D Barros, E Amaral, A Ramsey, T Sotnikova, M Ramirez & H Kim
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.08.005

  Abstract

• The Insulin/PI 3-Kinase Pathway Regulates Salt Chemotaxis Learning in Caenorhabditis elegans

  M Tomioka, T Adachi, H Suzuki, H Kunitomo, W Schafer & Y Iino
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.07.024

  Abstract

• Molecular Physiology of the Neural Circuit for Calcineurin-Dependent Associative Learning in Caenorhabditis elegans

  A. Kuhara
  Journal of Neuroscience 26
  (13 September 2006); doi:10.1523/JNEUROSCI.0517-06.2006

  Abstract

• TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity

  A. Bartolomucci
  Proceedings of the National Academy of Sciences 103
  (14 September 2006); doi:10.1073/pnas.0606102103

  Abstract

• Regulation of gene expression in the mammalian eye and its relevance to eye disease

  T. E. Scheetz
  Proceedings of the National Academy of Sciences 103
  (14 September 2006); doi:10.1073/pnas.0602562103

  Abstract

• On the art of identifying effective and specific siRNAs

  Yi Pei & Thomas Tuschl
  Nature Methods 3 670 - 676
  (23 August 2006); doi:10.1038/nmeth911

  Abstract

• Enhancing and confirming the specificity of RNAi experiments

  Bryan R Cullen
  Nature Methods 3 677 - 681
  (23 August 2006); doi:10.1038/nmeth913

  Abstract

• Tuning silence: conditional systems for RNA interference

  Maciej Wiznerowicz, Jolanta Szulc & Didier Trono
  Nature Methods 3 682 - 688
  (23 August 2006); doi:10.1038/nmeth914

  Abstract

• Expressing short hairpin RNAs in vivo

  Ola Snøve, Jr & John J Rossi
  Nature Methods 3 689 - 695
  (23 August 2006); doi:10.1038/nmeth927

  Abstract

• Genome-scale loss-of-function screening with a lentiviral RNAi library

  David E Root, Nir Hacohen, William C Hahn, Eric S Lander & David M Sabatini
  Nature Methods 3 715 - 719
  (23 August 2006); doi:10.1038/nmeth924

  Abstract

• A Genomic Screen for Modifiers of Tauopathy Identifies Puromycin-Sensitive Aminopeptidase as an Inhibitor of Tau-Induced Neurodegeneration

  S Karsten, T Sang, L Gehman, S Chatterjee, J Liu, G Lawless, S Sengupta, R Berry, J Pomakian & H Oh
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.07.019

  Abstract

• Identification of Sequence Motifs That Target Neuronal Nicotinic Receptors to Dendrites and Axons

  J. Xu
  Journal of Neuroscience 26
  (20 September 2006); doi:10.1523/JNEUROSCI.0840-06.2006

  Abstract

• Tumor Necrosis Factor Receptor 1 Is a Negative Regulator of Progenitor Proliferation in Adult Hippocampal Neurogenesis

  R. E. Iosif
  Journal of Neuroscience 26
  (20 September 2006); doi:10.1523/JNEUROSCI.2723-06.2006

  Abstract

• Neurotrophin-3 Gradients Established by Lentiviral Gene Delivery Promote Short-Distance Axonal Bridging beyond Cellular Grafts in the Injured Spinal Cord

  L. Taylor
  Journal of Neuroscience 26
  (20 September 2006); doi:10.1523/JNEUROSCI.0734-06.2006

  Abstract

• Identification of Sox17 as a Transcription Factor That Regulates Oligodendrocyte Development

  J. Sohn
  Journal of Neuroscience 26
  (20 September 2006); doi:10.1523/JNEUROSCI.1716-06.2006

  Abstract

• NMDA receptors are critical for unleashing consolidated auditory fear memories

  Cyrinne Ben Mamou, Karine Gamache & Karim Nader
  Nature Neuroscience 9 1237 - 1239
  (24 September 2006); doi:10.1038/nn1778

  Abstract

• Kinase activity of mutant LRRK2 mediates neuronal toxicity

  Wanli W Smith, Zhong Pei, Haibing Jiang, Valina L Dawson, Ted M Dawson & Christopher A Ross
  Nature Neuroscience 9 1231 - 1233
  (17 September 2006); doi:10.1038/nn1776

  Abstract

• Deficiency of hyccin, a newly identified membrane protein, causes hypomyelination and congenital cataract

  Federico Zara, Roberta Biancheri, Claudio Bruno, Laura Bordo, Stefania Assereto, Elisabetta Gazzerro, Federica Sotgia, Xiao Bo Wang, Stefania Gianotti, Silvia Stringara, Marina Pedemonte, Graziella Uziel, Andrea Rossi, Angelo Schenone, Paolo Tortori-donati, Marjo S Van der knaap, Michael P Lisanti & Carlo Minetti
  Nature Genetics 38 1111 - 1113
  (3 September 2006); doi:10.1038/ng1870

  Abstract

• Control of Peripheral Nerve Myelination by the  -Secretase BACE1

  M. Willem, A. N. Garratt, B. Novak, M. Citron, S. Kaufmann, A. Rittger, B. Destrooper, P. Saftig, C. Birchmeier & C. Haass
  Science 314
  (27 October 2006); doi:10.1126/science.1132341

  Abstract

• Presenilin-Dependent ErbB4 Nuclear Signaling Regulates the Timing of Astrogenesis in the Developing Brain

  S Sardi, J Murtie, S Koirala, B Patten & G Corfas
  Cell 127
  (6 October 2006); doi:10.1016/j.cell.2006.07.037

  Abstract

• Identification of a Novel Oligodendrocyte Cell Adhesion Protein Using Gene Expression Profiling

  J. A. Nielsen
  Journal of Neuroscience 26
  (27 September 2006); doi:10.1523/JNEUROSCI.2246-06.2006

  Abstract

• Targeted Deletion of a Single Sca8 Ataxia Locus Allele in Mice Causes Abnormal Gait, Progressive Loss of Motor Coordination, and Purkinje Cell Dendritic Deficits

  Y. He
  Journal of Neuroscience 26
  (27 September 2006); doi:10.1523/JNEUROSCI.2595-06.2006

  Abstract

• RTP801 Is Elevated in Parkinson Brain Substantia Nigral Neurons and Mediates Death in Cellular Models of Parkinson's Disease by a Mechanism Involving Mammalian Target of Rapamycin Inactivation

  C. Malagelada
  Journal of Neuroscience 26
  (27 September 2006); doi:10.1523/JNEUROSCI.3292-06.2006

  Abstract

• Activity- and mTOR-Dependent Suppression of Kv1.1 Channel mRNA Translation in Dendrites

  K. F. Raab-graham, P. C. G. Haddick, Y. N. Jan & L. Y. Jan
  Science 314
  (6 October 2006); doi:10.1126/science.1131693

  Abstract

• Local caspase activity directs engulfment of dendrites during pruning

  Darren W Williams, Shu Kondo, Agnieszka Krzyzanowska, Yasushi Hiromi & James W Truman
  Nature Neuroscience 9 1234 - 1236
  (17 September 2006); doi:10.1038/nn1774

  Abstract

• Asymmetrical -actin mRNA translation in growth cones mediates attractive turning to netrin-1

  Kin-Mei Leung, Francisca PG Van horck, Andrew C Lin, Rachel Allison, Nancy Standart & Christine E Holt
  Nature Neuroscience 9 1247 - 1256
  (17 September 2006); doi:10.1038/nn1775

  Abstract

• An essential role for -actin mRNA localization and translation in Ca²⁺-dependent growth cone guidance

  Jiaqi Yao, Yukio Sasaki, Zhexing Wen, Gary J Bassell & James Q Zheng
  Nature Neuroscience 9 1265 - 1273
  (17 September 2006); doi:10.1038/nn1773

  Abstract

• Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

  Alfredo Ramirez, André Heimbach, Jan Gründemann, Barbara Stiller, Dan Hampshire, L Pablo Cid, Ingrid Goebel, Ammar F Mubaidin, Abdul-Latif Wriekat, Jochen Roeper, Amir Al-din, Axel M Hillmer, Meliha Karsak, Birgit Liss, C Geoffrey Woods, Maria I Behrens & Christian Kubisch
  Nature Genetics 38 1184 - 1191
  (10 September 2006); doi:10.1038/ng1884

  Abstract

• Starvation Induces cAMP Response Element-Binding Protein-Dependent Gene Expression through Octopamine-Gq Signaling in Caenorhabditis elegans

  S. Suo, Y. Kimura & H. H. M. Van tol
  Journal of Neuroscience 26
  (4 October 2006); doi:10.1523/JNEUROSCI.0819-06.2006

  Abstract

• Functional Role of GABAergic Innervation of the Cochlea: Phenotypic Analysis of Mice Lacking GABAA Receptor Subunits  1,  2,  5,  6, beta2, beta3, or  

  S. F. Maison, T. W. Rosahl, G. E. Homanics & M. C. Liberman
  Journal of Neuroscience 26
  (4 October 2006); doi:10.1523/JNEUROSCI.2395-06.2006

  Abstract

• Bidirectional Trafficking of Prostaglandin E2 Receptors Involved in Long-Term Potentiation in Visual Cortex

  Y. Akaneya & T. Tsumoto
  Journal of Neuroscience 26
  (4 October 2006); doi:10.1523/JNEUROSCI.3028-06.2006

  Abstract

• Genetic Contributions to Human Brain Morphology and Intelligence

  H. E. Hulshoff pol, H. G. Schnack, D. Posthuma, R. C. W. Mandl, W. F. Baare, C. Van oel, N. E. Van haren, D. L. Collins, A. C. Evans, K. Amunts, U. Burgel, K. Zilles, E. De geus, D. I. Boomsma & R. S. Kahn
  Journal of Neuroscience 26
  (4 October 2006); doi:10.1523/JNEUROSCI.1312-06.2006

  Abstract

• Neuronal Activity of Histaminergic Tuberomammillary Neurons During Wake-Sleep States in the Mouse

  K. Takahashi, J.-S. Lin & K. Sakai
  Journal of Neuroscience 26
  (4 October 2006); doi:10.1523/JNEUROSCI.2341-06.2006

  Abstract

• Effects in Neocortical Neurons of Mutations of the Nav1.2 Na+ Channel causing Benign Familial Neonatal-Infantile Seizures

  P. Scalmani, R. Rusconi, E. Armatura, F. Zara, G. Avanzini, S. Franceschetti & M. Mantegazza
  Journal of Neuroscience 26
  (4 October 2006); doi:10.1523/JNEUROSCI.2476-06.2006

  Abstract

• Expression of Phox2b by Brainstem Neurons Involved in Chemosensory Integration in the Adult Rat

  R. L. Stornetta, T. S. Moreira, A. C. Takakura, B. J. Kang, D. A. Chang, G. H. West, J. F. Brunet, D. K. Mulkey, D. A. Bayliss & P. G. Guyenet
  Journal of Neuroscience 26
  (4 October 2006); doi:10.1523/JNEUROSCI.2917-06.2006

  Abstract

• From the Cover: miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation

  H.-J. Lee, M. Palkovits & W. S. Young
  Proceedings of the National Academy of Sciences 103
  (17 October 2006); doi:10.1073/pnas.0605781103

  Abstract

• A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes

  K. Wada, J. T. Howard, P. Mcconnell, O. Whitney, T. Lints, M. V. Rivas, H. Horita, M. A. Patterson, S. A. White, C. Scharff, S. Haesler, S. Zhao, H. Sakaguchi, M. Hagiwara, T. Shiraki, T. Hirozane-kishikawa, P. Skene, Y. Hayashizaki, P. Carninci & E. D. Jarvis
  Proceedings of the National Academy of Sciences 103
  (10 October 2006); doi:10.1073/pnas.0607098103

  Abstract

• Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice

  P. Sgado, L. Alberi, D. Gherbassi, S. L. Galasso, G. M. J. Ramakers, K. N. Alavian, M. P. Smidt, R. H. Dyck & H. H. Simon
  Proceedings of the National Academy of Sciences 103
  (10 October 2006); doi:10.1073/pnas.0602116103

  Abstract

• Inaugural Article: wasted away, a Drosophila mutation in triosephosphate isomerase, causes paralysis, neurodegeneration, and early death

  J. P. Gnerer, R. A. Kreber & B. Ganetzky
  Proceedings of the National Academy of Sciences 103
  (10 October 2006); doi:10.1073/pnas.0606887103

  Abstract

• Jie Wu & Xiaohui Xie
  Genome Biology 7
  (1 January 2006); doi:10.1186/gb-2006-7-9-r85

  Abstract

• Vinsensius B Vega, Chin-Yo Lin, Koon Lai, Say Li kong, Min Xie, Xiaodi Su, Huey Teh, Jane S Thomsen, Ai Li yeo, Wing Sung, Guillaume Bourque & Edison T Liu
  Genome Biology 7
  (1 January 2006); doi:10.1186/gb-2006-7-9-r82

  Abstract

• Genomic Rearrangements and Gene Copy-Number Alterations as a Cause of Nervous System Disorders

  J Lee & J Lupski
  Neuron 52
  (5 October 2006); doi:10.1016/j.neuron.2006.09.027

  Abstract

• The Neurobiology of Multiple Sclerosis: Genes, Inflammation, and Neurodegeneration

  S Hauser & J Oksenberg
  Neuron 52
  (5 October 2006); doi:10.1016/j.neuron.2006.09.011

  Abstract

• From genes to behavior in developmental dyslexia

  Albert M Galaburda, Joseph Loturco, Franck Ramus, R Holly Fitch & Glenn D Rosen
  Nature Neuroscience 9 1213 - 1217
  (26 September 2006); doi:10.1038/nn1772

  Abstract

• Fragile X syndrome and autism at the intersection of genetic and neural networks

  Matthew K Belmonte & Thomas Bourgeron
  Nature Neuroscience 9 1221 - 1225
  (26 September 2006); doi:10.1038/nn1765

  Abstract

• Time to give up on a single explanation for autism

  Francesca Happé, Angelica Ronald & Robert Plomin
  Nature Neuroscience 9 1218 - 1220
  (26 September 2006); doi:10.1038/nn1770

  Abstract