September 2007

• Chemosensation: Sensing sugar in the brain

  Standfirst

  In normal but not obese mice, glucose increases the firing rate of hypothalamic pro-opiomelanocortin neurons.

  Leonie Welberg
  Nature Reviews Neuroscience 8 738 - 739
  doi:10.1038/nrn2244

• Neurodegenerative disease: Micromanaging dopamine neurons

  Standfirst

  The microRNA miR-133b is important in dopamine neuron function.

  Katherine Whalley
  Nature Reviews Neuroscience 8 735
  doi:10.1038/nrn2246

• Synapse stabilization: A complex story

  Standfirst

  Complex regulation of the ubiquitin-proteasome system mediates synapse stabilization and elimination in C. elegans.

  Katherine Whalley
  Nature Reviews Neuroscience 8 652 - 653
  doi:10.1038/nrn2217

• Vesicular trafficking: The endocytic puzzle

  Standfirst

  In Drosophila, Eps15 is important in both endocytosis and synapse development.

  Claudia Wiedemann
  Nature Reviews Neuroscience 8 652 - 653
  doi:10.1038/nrn2227

• Obesity: Stress and obesity connect at NPY

  Standfirst

  Stress-induced neuropeptide Y release increases peripheral fat deposits.

  Alexandra Flemming
  Nature Reviews Drug Discovery 6 701
  doi:10.1038/nrd2408

• Development: The origins of interneuron diversity

  Standfirst

  An interneuron's birth date may determine its molecular and physiological phenotype.

  Katherine Whalley
  Nature Reviews Neuroscience 8 655
  doi:10.1038/nrn2225

• Learning and memory: Forgetting the fear

  Standfirst

  Hippocampal cyclin-dependent kinase 5 regulates the loss of fearful associations.

  Leonie Welberg
  Nature Reviews Neuroscience 8 651
  doi:10.1038/nrn2223

• Putting a trace on metabolites

  Standfirst

  Two independent groups describe isotopic labeling methods for detecting small-molecule metabolites for different applications.

  Allison Doerr
  Nature Methods 4 684 - 685
  doi:10.1038/nmeth0907-684b