Electrophysiology

• Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family

  Ho, A. et al.
  The Journal of Neuroscience 2613089-13101
  doi:10.1523/JNEUROSCI.2855-06.2006

  Abstract

• Progressive Deafness and Altered Cochlear Innervation in Knock-Out Mice Lacking Prosaposin

  Akil, O. et al.
  The Journal of Neuroscience 2613076-13088
  doi:10.1523/JNEUROSCI.3746-06.2006

  Abstract

• Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy

  Klaassen, A. et al.
  PNAS 103 19152-19157
  (4 December 2006); doi:10.1073/pnas.0608215103

  Abstract

• Hyperekplexia Phenotype of Glycine Receptor α1 Subunit Mutant Mice Identifies Z²⁺ as an Essential Endogenous Modulator of Glycinergic Neurotransmission

  Hirzel, K. et al.
  Neuron 52
  (22 November 2006); doi:10.1016/j.neuron.2006.09.035

  Abstract

• The ducky2J Mutation in Cacna2d2 Results in Reduced Spontaneous Purkinje Cell Activity and Altered Gene Expression

  Donato, R. et al.
  Journal of Neuroscience 26
  (29 November 2006); doi:10.1523/JNEUROSCI.3080-06.2006

  Abstract

• Deletion of Kv4.2 Gene Eliminates Dendritic A-Type K+ Current and Enhances Induction of Long-Term Potentiation in Hippocampal CA1 Pyramidal Neurons

  Chen, X. et al.
  Journal of Neuroscience 26
  (22 November 2006); doi:10.1523/JNEUROSCI.2667-06.2006

  Abstract

• Distinct Populations of Spinal Cord Lamina II Interneurons Expressing G-Protein-Gated Potassium Channels

  Marker, C. L., Luján, R., Colón, J. & Wickman, K.
  Journal of Neuroscience 26
  (22 November 2006); doi:10.1523/JNEUROSCI.3693-06.2006

  Abstract

• The TRPM7 Ion Channel Functions in Cholinergic Synaptic Vesicles and Affects Transmitter Release

  Krapivinsky, G., Mochida, S., Krapivinsky, L., Cibulsky, S. M. & Clapham, D. E.
  Neuron 52
  (9 November 2006); doi:10.1016/j.neuron.2006.09.033

  Abstract

• Arc/Arg3.1 Is Essential for the Consolidation of Synaptic Plasticity and Memories

  Plath, N. et al.
  Neuron 52
  (9 November 2006); doi:10.1016/j.neuron.2006.08.024

  Abstract

• Arc/Arg3.1 Mediates Homeostatic Synaptic Scaling of AMPA Receptors

  Shepherd, J. D. et al.
  Neuron 52
  (9 November 2006); doi:10.1016/j.neuron.2006.08.034

  Abstract

• Increased Expression of the Immediate-Early Gene Arc/Arg3.1 Reduces AMPA Receptor-Mediated Synaptic Transmission

  Rial Verde, E. M., Lee-Osbourne, J., Worley, P. F., Malinow, R. & Cline, H. T.
  Neuron 52
  (9 November 2006); doi:10.1016/j.neuron.2006.09.031

  Abstract

• Vesicular Glutamate Transporter VGLUT2 Expression Levels Control Quantal Size and Neuropathic Pain

  Moechars, D. et al.
  Journal of Neuroscience 26
  (15 November 2006); doi:10.1523/JNEUROSCI.2556-06.2006

  Abstract

• CLC-3 Channels Modulate Excitatory Synaptic Transmission in Hippocampal Neurons

  Wang, X. Q. et al.
  Neuron 52
  (18 October 2006); doi:10.1016/j.neuron.2006.08.035

  Abstract

• Distinct Roles of the beta1-Class Integrins at the Developing and the Mature Hippocampal Excitatory Synapse

  Huang, Z. et al.
  Journal of Neuroscience 26
  (25 October 2006); doi:10.1523/JNEUROSCI.3526-06.2006

  Abstract

• μO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

  Ekberg, J. et al.
  Proceedings of the National Academy of Sciences 103
  (31 October 2006); doi:10.1073/pnas.0601819103

  Abstract

• Deletion of Annexin 2 Light Chain p11 in Nociceptors Causes Deficits in Somatosensory Coding and Pain Behavior

  Foulkes, T. et al.
  Journal of Neuroscience
  (11 October 2006); doi:10.1523/JNEUROSCI.1997-06.2006

  Abstract

• NGL family PSD-95–interacting adhesion molecules regulate excitatory synapse formation

  Seho Kim, Alain Burette, Hye Sun Chung, Seok-Kyu Kwon, Jooyeon Woo, Hyun Woo Lee, Karam Kim, Hyun Kim, Richard J Weinberg and Eunjoon Kim
  Nature Neuroscience 9 1294 - 1301
  (17 September 2006); doi:10.1038/nn1763

  Abstract

• Bidirectional Trafficking of Prostaglandin E2 Receptors Involved in Long-Term Potentiation in Visual Cortex

  Akaneya, Y. & Tsumoto, T.
  Journal of Neuroscience
  (4 October 2006); doi:10.1523/JNEUROSCI.3028-06.2006

  Abstract

• Neuronal Activity of Histaminergic Tuberomammillary Neurons During Wake-Sleep States in the Mouse

  Takahashi, K., Lin, J. & Sakai, K.
  Journal of Neuroscience
  (4 October 2006); doi:10.1523/JNEUROSCI.2341-06.2006

  Abstract

• Effects in Neocortical Neurons of Mutations of the Nav1.2 Na+ Channel causing Benign Familial Neonatal-Infantile Seizures

  Scalmani, P. et al.
  Journal of Neuroscience
  (4 October 2006); doi:10.1523/JNEUROSCI.2476-06.2006

  Abstract

• Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations

  Tu, H. et al.
  Cell 126
  (8 September 2006); doi:10.1016/j.cell.2006.06.059

  Abstract

• The Prototoxin lynx1 Acts on Nicotinic Acetylcholine Receptors to Balance Neuronal Activity and Survival In Vivo

  Miwa, J. M. et al.
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.07.025

  Abstract

• Knockdown of Nav 1.6a Na+ channels affects zebrafish motoneuron development

  Pineda, R. H. et al.
  Development 133
  (30 August 2006); doi:10.1242/dev.02559

  Abstract

• Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

  Frank H Yu, Massimo Mantegazza, Ruth E Westenbroek, Carol A Robbins, Franck Kalume, Kimberly A Burton, William J Spain, G Stanley McKnight, Todd Scheuer and William A Catterall
  Nature Neuroscience 9 1142 - 1149
  (20 August 2006); doi:10.1038/nn1754

  Abstract

• RGS2 Determines Short-Term Synaptic Plasticity in Hippocampal Neurons by Regulating Gi/o- Mediated Inhibition of Presynaptic Ca2+ Channels

  Han, J. et al.
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.07.012

  Abstract

• Mice Deficient for the Vesicular Acetylcholine Transporter Are Myasthenic and Have Deficits in Object and Social Recognition

  Prado, V. F. et al.
  Neuron 51
  (7 September 2006); doi:10.1016/j.neuron.2006.08.005

  Abstract

• The cells and logic for mammalian sour taste detection

  Angela L. Huang, Xiaoke Chen, Mark A. Hoon, Jayaram Chandrashekar, Wei Guo, Dimitri Tränkner, Nicholas J. P. Ryba and Charles S. Zuker
  Nature 442 934 - 938
  doi:10.1038/nature05084

  Abstract

• Altered Hippocampal Synaptic Potentiation in P2X4 Knock-Out Mice

  Sim, J. A. et al.
  Journal of Neuroscience 26
  (30 August 2006); doi:10.1523/JNEUROSCI.2370-06.2006

  Abstract

• Transient Receptor Potential Vanilloid 1 Is Required for Intrinsic Osmoreception in Organum Vasculosum Lamina Terminalis Neurons and for Normal Thirst Responses to Systemic Hyperosmolality

  Ciura, S. & Bourque, C. W.
  Journal of Neuroscience 26
  (20 August 2006); doi:10.1523/JNEUROSCI.0877-06.2006

  Abstract

• Contrasting Roles of Corticosteroid Receptors in Hippocampal Plasticity

  Avital, A., Segal, M. & Richter-Levin, G.
  Journal of Neuroscience 26
  (6 September 2006); doi:10.1523/JNEUROSCI.1628-06.2006

  Abstract

• Deletion of the GABAA Receptor  1 Subunit Increases Tonic GABAA Receptor Current: A Role for GABA Uptake Transporters

  Ortinski, P. I. et al.
  Journal of Neuroscience 26
  (6 September 2006); doi:10.1523/JNEUROSCI.2610-06.2006

  Abstract

• The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus

  Monory, K. et al.
  Neuron 51
  (17 August 2006); doi:10.1016/j.neuron.2006.07.006

  Abstract

• NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus

  Ayumu Tashiro, Vladislav M. Sandler, Nicolas Toni, Chunmei Zhao and Fred H. Gage
  Nature 442 929 - 933
  (13 August 2006); doi:10.1038/nature05028

  Abstract

• BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output

  Andrea L Meredith, Steven W Wiler, Brooke H Miller, Joseph S Takahashi, Anthony A Fodor, Norman F Ruby and Richard W Aldrich
  Nature Neuroscience 9 1041
  doi:10.1038/nn1740

  Abstract

• BDNF-mediated neurotransmission relies upon a myosin VI motor complex

  Hiroko Yano, Ipe Ninan, Hong Zhang, Teresa A Milner, Ottavio Arancio and Moses V Chao
  Nature Neuroscience
  (2 July 2006); doi:10.1038/nn1730

  Abstract

• Dynamic Translational and Proteasomal Regulation of Fragile X Mental Retardation Protein Controls mGluR-Dependent Long-Term Depression

  Hou, L. et al.
  Neuron 51
  (16 August 2006); doi:10.1016/j.neuron.2006.07.005

  Abstract

• MuSK Expressed in the Brain Mediates Cholinergic Responses, Synaptic Plasticity, and Memory Formation

  Garcia-Osta, A. et al.
  Journal of Neuroscience 26
  (26 July 2006); doi:10.1523/JNEUROSCI.1674-06.2006

  Abstract

• P2X receptors as cell-surface ATP sensors in health and disease

  Baljit S. Khakh and R. Alan North
  Nature 442 527 - 532
  doi:10.1038/nature04886

  Abstract

• In Vivo Two-Photon Imaging Reveals a Role of Arc in Enhancing Orientation Specificity in Visual Cortex

  Wang, K. H. et al.
  Cell 126
  (28 July 2006); doi:10.1016/j.cell.2006.06.038

  Abstract

• AMPA receptors regulate experience-dependent dendritic arbor growth in vivo

  Haas, K., Li, J. & Cline, H. T.
  Proceedings of the National Academy of Sciences 103
  (1 August 2006); doi:10.1073/pnas.0602670103

  Abstract

• Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice

  Weisstaub, N. V. et al.
  Science 313
  (28 July 2006); doi:10.1126/science.1123432

  Abstract

• Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake

  Heisler, L. K. et al.
  Neuron 51
  (20 July 2006); doi:10.1016/j.neuron.2006.06.004

  Abstract

• The Glutamate-Aspartate Transporter GLAST Mediates Glutamate Uptake at Inner Hair Cell Afferent Synapses in the Mammalian Cochlea

  Glowatzki, E. et al.
  Journal of Neuroscience 26
  (19 July 2006); doi:10.1523/JNEUROSCI.1545-06.2006

  Abstract

• Dihydropyridine Receptors and Type 1 Ryanodine Receptors Constitute the Molecular Machinery for Voltage-Induced Ca2+ Release in Nerve Terminals

  De Crescenzo, V. et al.
  Journal of Neuroscience 26
  (29 July 2006); doi:10.1523/JNEUROSCI.1512-06.2006

  Abstract

• Visual Experience Regulates Metabotropic Glutamate Receptor-Mediated Plasticity of AMPA Receptor Synaptic Transmission by Homer1a Induction

  Van Keuren-Jensen, K. & Cline, H. T.
  Journal of Neuroscience 26
  (19 July 2006); doi:10.1523/JNEUROSCI.5083-05.2006

  Abstract

• Terminal Nerve-Derived Neuropeptide Y Modulates Physiological Responses in the Olfactory Epithelium of Hungry Axolotls (Ambystoma mexicanum)

  Mousley, A., Polese, G., Marks, N. J. & Eisthen, H. L.
  Journal of Neuroscience 26
  (19 July 2006); doi:10.1523/JNEUROSCI.1977-06.2006

  Abstract

• Dopamine D1/D5 Receptors Gate the Acquisition of Novel Information through Hippocampal Long-Term Potentiation and Long-Term Depression

  Lemon, N. & Manahan-Vaughan, D.
  Journal of Neuroscience 26
  (19 July 2006); doi:10.1523/JNEUROSCI.1454-06.2006

  Abstract

• Expression and Function of SNAP-25 as a Universal SNARE Component in GABAergic Neurons

  Tafoya, L. C. R. et al.
  Journal of Neuroscience 26
  (26 July 2006); doi:10.1523/JNEUROSCI.1866-06.2006

  Abstract

• Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins

  Moriguchi, S. et al.
  Proceedings of the National Academy of Sciences 103
  (29 June 2006); doi:10.1073/pnas.0509863103

  Abstract

• Altered Balance of Glutamatergic/GABAergic Synaptic Input and Associated Changes in Dendrite Morphology after BDNF Expression in BDNF-Deficient Hippocampal Neurons

  Singh, B. et al.
  Journal of Neuroscience 26
  (5 July 2006); doi:10.1523/JNEUROSCI.5474-05.2006

  Abstract

• Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein

  Priller, C. et al.
  Journal of Neuroscience 26
  (5 July 2006); doi:10.1523/JNEUROSCI.1450-06.2006

  Abstract

• Alternative N-Terminal Domains of PSD-95 and SAP97 Govern Activity-Dependent Regulation of Synaptic AMPA Receptor Function

  Schlüter, O. M, Xu, W. & Malenka, R. C.
  Neuron 51
  (6 July 2006); doi:10.1016/j.neuron.2006.05.016

  Abstract

• Kinase Suppressor of Ras1 Compartmentalizes Hippocampal Signal Transduction and Subserves Synaptic Plasticity and Memory Formation

  Shalin, S. C., Hernandez, C. M., Dougherty, M. K., Morrison, D. K. & Sweatt, J. D.
  Neuron 50
  (1 June 2006); doi:10.1016/j.neuron.2006.04.029

  Abstract

• Hierarchical Control of Dopamine Neuron-Firing Patterns by Nicotinic Receptors

  Mameli-Engvall, M. et al.
  Neuron 50
  (14 June 2006); doi:10.1016/j.neuron.2006.05.007

  Abstract

• Genome-wide RNAi screen of Ca2+ influx identifies genes that regulate Ca2+ release-activated Ca2+ channel activity

  Zhang, S. L. et al.
  Proceedings of the National Academy of Sciences 103
  (2 June 2006); doi:10.1073/pnas.0603161103

  Abstract

• Anomalous levels of Cl- transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory

  Palma, E. et al.
  Proceedings of the National Academy of Sciences 103
  (30 May 2006); doi:10.1073/pnas.0602979103

  Abstract

• A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons

  Rush, A. M. et al.
  Proceedings of the National Academy of Sciences 103
  (15 May 2006); doi:10.1073/pnas.0602813103

  Abstract

• Modulation of Basal and Receptor-Induced GIRK Potassium Channel Activity and Neuronal Excitability by the Mammalian PINS Homolog LGN

  Wiser, O. et al.
  Neuron 50
  (17 May 2006); doi:10.1016/j.neuron.2006.03.046

  Abstract

• Differential Compartmentalization and Distinct Functions of GABAB Receptor Variants

  Vigot, R. et al.
  Neuron 50
  (17 May 2006); doi:10.1016/j.neuron.2006.04.014

  Abstract

• The GABAB1b Isoform Mediates Long-Lasting Inhibition of Dendritic Ca2+ Spikes in Layer 5 Somatosensory Pyramidal Neurons

  Párez-Garci, E., Gassmann, M., Bettler, B. & Larkum, M. E.
  Neuron 50
  (17 May 2006); doi:10.1016/j.neuron.2006.04.019

  Abstract

• Miniature Neurotransmission Stabilizes Synaptic Function via Tonic Suppression of Local Dendritic Protein Synthesis

  Sutton, M. A. et al.
  Cell 125
  (18 May 2006); doi:10.1016/j.cell.2006.03.040

  Abstract

• A small-molecule screen in C. elegans yields a new calcium channel antagonist

  Trevor C. Y. Kwok, Nicole Ricker, Regina Fraser, Allen W. Chan, Andrew Burns, Elise F. Stanley, Peter McCourt, Sean R. Cutler and Peter J. Roy
  Nature 441 91 - 95
  doi:10.1038/nature04657

  Abstract

• Synaptic scaling mediated by glial TNF-

  David Stellwagen and Robert C. Malenka
  Nature 440 1054 - 1059
  (19 March 2006); doi:10.1038/nature04671

  Abstract

• Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes

  Michael F Waters, Natali A Minassian, Giovanni Stevanin, Karla P Figueroa, John P A Bannister, Dagmar Nolte, Allan F Mock, Virgilio Gerald H Evidente, Dominic B Fee, Ulrich Müller, Alexandra Dürr, Alexis Brice, Diane M Papazian and Stefan M Pulst
  Nature Genetics 38 447 - 451
  (26 February 2006); doi:10.1038/ng1758

  Abstract

• A mint of mutations in TRPM8 leads to cool results

  Craig Montell
  Nature Neuroscience 9 466 - 468
  doi:10.1038/nn0406-466

  Abstract

• High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol

  Michael Bandell, Adrienne E Dubin, Matt J Petrus, Anthony Orth, Jayanti Mathur, Sun Wook Hwang and Ardem Patapoutian
  Nature Neuroscience 9 493 - 500
  (5 March 2006); doi:10.1038/nn1665

  Abstract

• BDNF-dependent synaptic sensitization in midbrain dopamine neurons after cocaine withdrawal

  Lu Pu, Qing-song Liu and Mu-ming Poo
  Nature Neuroscience 9 605 - 607
  (23 April 2006); doi:10.1038/nn1687

  Abstract

• Correlating whisker behavior with membrane potential in barrel cortex of awake mice

  Sylvain Crochet and Carl C H Petersen
  Nature Neuroscience 9 608 - 610
  (16 April 2006); doi:10.1038/nn1690

  Abstract