Electrophysiology

• Phosphatidylinositol 3-Kinase Is a Key Mediator of Central Sensitization in Painful Inflammatory Conditions

  S. Pezet, F. Marchand, R. D'Mello, J. Grist, A. K. Clark, M. Malcangio, A. H. Dickenson, R. J. Williams & S. B. McMahon
  Journal of Neuroscience 28
  (16 April 2008); doi:10.1523/JNEUROSCI.5392-07.2008

  Abstract

• Setting Clock Speed in Mammals: The CK1ε tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins

  Q Meng, L Logunova, E Maywood, M Gallego, J Lebiecki, T Brown, M Sládek, A Semikhodskii, N Glossop & H Piggins
  Neuron 58
  (10 April 2008); doi:10.1016/j.neuron.2008.01.019

  Abstract

• Transgenic Mice Lacking NMDAR-Dependent LTD Exhibit Deficits in Behavioral Flexibility

  R Nicholls, J Alarcon, G Malleret, R Carroll, M Grody, S Vronskaya & E Kandel
  Neuron 58
  (10 April 2008); doi:10.1016/j.neuron.2008.01.039

  Abstract

• Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission

  M. Heine, L. Groc, R. Frischknecht, J.-C. Béïque, B. Lounis, G. Rumbaugh, R. L. Huganir, L. Cognet & D. Choquet
  Science 320
  (11 April 2008); doi:10.1126/science.1152089

  Abstract

• Lateral presynaptic inhibition mediates gain control in an olfactory circuit

  Shawn R. Olsen & Rachel I. Wilson
  Nature 452 956 - 960
  (16 March 2008); doi:10.1038/nature06864

  Abstract

• Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels

  Dieter Wicher, Ronny Schäfer, René Bauernfeind, Marcus C. Stensmyr, Regine Heller, Stefan H. Heinemann & Bill S. Hansson
  Nature 452 1007 - 1011
  (13 April 2008); doi:10.1038/nature06861

  Abstract

• Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter

  Ragnhildur Káradóttir, Nicola B Hamilton, Yamina Bakiri & David Attwell
  Nature Neuroscience 11 450 - 456
  (2 March 2008); doi:10.1038/nn2060

  Abstract

• Rapid Encoding and Perception of Novel Odors in the Rat

  Daniel W. Wesson, Ryan M. Carey, Justus V. Verhagen, Matt Wachowiak & Howard B. Eichenbaum
  PLoS Biology 6
  (8 April 2008); doi:10.1371/journal.pbio.0060082

  Abstract

• Endocannabinoids Mediate Neuron-Astrocyte Communication

  M Navarrete & A Araque
  Neuron 57
  (27 March 2008); doi:10.1016/j.neuron.2008.01.029

  Abstract

• mGluR1/5-Dependent Long-Term Depression Requires the Regulated Ectodomain Cleavage of Neuronal Pentraxin NPR by TACE

  R Cho, J Park, S Wolff, D Xu, C Hopf, J Kim, R Reddy, R Petralia, M Perin & D Linden
  Neuron 57
  (27 March 2008); doi:10.1016/j.neuron.2008.01.010

  Abstract

• Insect Odorant Receptors Are Molecular Targets of the Insect Repellent DEET

  M. Ditzen, M. Pellegrino & L. B. Vosshall
  Science 319
  (28 March 2008); doi:10.1126/science.1153121

  Abstract

• Ivy Cells: A Population of Nitric-Oxide-Producing, Slow-Spiking GABAergic Neurons and Their Involvement in Hippocampal Network Activity

  P Fuentealba, R Begum, M Capogna, S Jinno, L Marton, J Csicsvari, A Thomson, P Somogyi & T Klausberger
  Neuron 57
  (27 March 2008); doi:10.1016/j.neuron.2008.01.034

  Abstract

• Differential Mechanisms of CRF1 and CRF2 Receptor Functions in the Amygdala in Pain-Related Synaptic Facilitation and Behavior

  Y. Fu & V. Neugebauer
  Journal of Neuroscience 28
  (9 April 2008); doi:10.1523/JNEUROSCI.0227-08.2008

  Abstract

• Absence and Rescue of Morphine Withdrawal in GIRK/Kir3 Knock-out Mice

  H. G. Cruz, F. Berton, M. Sollini, C. Blanchet, M. Pravetoni, K. Wickman & C. Luscher
  Journal of Neuroscience 28
  (9 April 2008); doi:10.1523/JNEUROSCI.0267-08.2008

  Abstract

• Absence of Functional Peroxisomes from Mouse CNS Causes Dysmyelination and Axon Degeneration

  L. Hulshagen, O. Krysko, A. Bottelbergs, S. Huyghe, R. Klein, P. P. Van Veldhoven, P. P. De Deyn, R. D'Hooge, D. Hartmann & M. Baes
  Journal of Neuroscience 28
  (9 April 2008); doi:10.1523/JNEUROSCI.4968-07.2008

  Abstract

• Alterations in Ca²⁺-Buffering in Prion-Null Mice: Association with Reduced Afterhyperpolarizations in CA1 Hippocampal Neurons

  A. D. Powell, E. C. Toescu, J. Collinge & J. G. R. Jefferys
  Journal of Neuroscience 28
  (9 April 2008); doi:10.1523/JNEUROSCI.0675-08.2008

  Abstract

• Somatostatin Receptor Subtype 4 Couples to the M-Current to Regulate Seizures

  C. Qiu, T. Zeyda, B. Johnson, U. Hochgeschwender, L. de Lecea & M. K. Tallent
  Journal of Neuroscience 28
  (2 April 2008); doi:10.1523/JNEUROSCI.4679-07.2008

  Abstract

• Glycinergic and GABA_A-Mediated Inhibition of Somatic Motoneurons Does Not Mediate Rapid Eye Movement Sleep Motor Atonia

  P. L. Brooks & J. H. Peever
  Journal of Neuroscience 28
  (2 April 2008); doi:10.1523/JNEUROSCI.5023-07.2008

  Abstract

• Food Reward in the Absence of Taste Receptor Signaling

  I de Araujo, A Oliveiramaia, T Sotnikova, R Gainetdinov, M Caron, M Nicolelis & S Simon
  Neuron 57
  (27 March 2008); doi:10.1016/j.neuron.2008.01.032

  Abstract

• TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal Interneurons

  H Gibson et al.
  Neuron 57
  (13 March 2008); doi:10.1016/j.neuron.2007.12.027

  Abstract

• Hypocretin-1 Potentiates NMDA Receptor-Mediated Somatodendritic Secretion from Locus Ceruleus Neurons

  X.-W. Chen, Y. Mu, H.-P. Huang, N. Guo, B. Zhang, S.-Y. Fan, J.-X. Xiong, S.-R. Wang, W. Xiong, W. Huang, T. Liu, L.-H. Zheng, C. X. Zhang, L.-H. Li, Z.-P. Yu, Z.-A. Hu & Z. Zhou
  Journal of Neuroscience 28
  (19 March 2008); doi:10.1523/JNEUROSCI.4426-07.2008

  Abstract

• Compartmentalized dendritic plasticity and input feature storage in neurons

  Attila Losonczy, Judit K. Makara & Jeffrey C. Magee
  Nature 452 436 - 441
  doi:10.1038/nature06725

  Abstract

• A Putative Cation Channel, NCA-1, and a Novel Protein, UNC-80, Transmit Neuronal Activity in C. elegans

  Edward Yeh, Sharon Ng, Mi Zhang, Magali Bouhours, Ying Wang, Min Wang, Wesley Hung, Kyota Aoyagi, Katya Melnik-martinez, Michelle Li, Fang Liu, William R. Schafer & Mei Zhen
  PLoS Biology 6
  (1 January 2008); doi:10.1371/journal.pbio.0060055

  Abstract

• The Crucial Role of Chromogranins in Storage and Exocytosis Revealed Using Chromaffin Cells from Chromogranin A Null Mouse

  M. S. Montesinos, J. D. Machado, M. Camacho, J. Diaz, Y. G. Morales, D. Alvarez de la rosa, E. Carmona, A. Castaneyra, O. H. Viveros, D. T. O'connor, S. K. Mahata & R. Borges
  Journal of Neuroscience 28
  (26 March 2008); doi:10.1523/JNEUROSCI.5292-07.2008

  Abstract

• Synaptic Function for the Nogo-66 Receptor NgR1: Regulation of Dendritic Spine Morphology and Activity-Dependent Synaptic Strength

  H. Lee, S. J. Raiker, K. Venkatesh, R. Geary, L. A. Robak, Y. Zhang, H. H. Yeh, P. Shrager & R. J. Giger
  Journal of Neuroscience 28
  (12 March 2008); doi:10.1523/JNEUROSCI.5586-07.2008

  Abstract

• Genetic Control of Circuit Function: Vsx1 and Irx5 Transcription Factors Regulate Contrast Adaptation in the Mouse Retina

  D. Kerschensteiner, H. Liu, C. W. Cheng, J. Demas, S. H. Cheng, C.-c. Hui, R. L. Chow & R. O. L. Wong
  Journal of Neuroscience 28
  (5 March 2008); doi:10.1523/JNEUROSCI.4784-07.2008

  Abstract

• Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

  Alexis M Stranahan, Thiruma V Arumugam, Roy G Cutler, Kim Lee, Josephine M Egan & Mark P Mattson
  Nature Neuroscience 11 309 - 317
  (17 February 2008); doi:10.1038/nn2055

  Abstract

• Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

  A. Y. Hung, K. Futai, C. Sala, J. G. Valtschanoff, J. Ryu, M. A. Woodworth, F. L. Kidd, C. C. Sung, T. Miyakawa, M. F. Bear, R. J. Weinberg & M. Sheng
  Journal of Neuroscience 28
  (13 February 2008); doi:10.1523/jneurosci.3032-07.2008

  Abstract

• A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic

  Héctor Salazar, Itzel Llorente, Andrés Jara-Oseguera, Refugio García-Villegas, Mika Munari, Sharona E Gordon, León D Islas & Tamara Rosenbaum
  Nature Neuroscience 11 255 - 261
  (24 February 2008); doi:10.1038/nn2056

  Abstract

• Synapse-Specific Expression of Functional Presynaptic NMDA Receptors in Rat Somatosensory Cortex

  D. J. Brasier & D. E. Feldman
  Journal of Neuroscience 28
  (27 February 2008); doi:10.1523/JNEUROSCI.3915-07.2008

  Abstract

• Enhanced Cortico-Amygdala Efficacy and Suppressed Fear in Absence of Rap1

  B.-X. Pan, F. Vautier, W. Ito, V. Y. Bolshakov & A. Morozov
  Journal of Neuroscience 28
  (27 February 2008); doi:10.1523/JNEUROSCI.5156-07.2008

  Abstract

• Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice

  M Pennuto, E Tinelli, M Malaguti, U Del Carro, M D'Antonio, D Ron, A Quattrini, M Feltri & L Wrabetz
  Neuron 57
  (7 February 2008); doi:10.1016/j.neuron.2007.12.021

  Abstract

• Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep

  Vladyslav V Vyazovskiy, Chiara Cirelli, Martha Pfister-Genskow, Ugo Faraguna & Giulio Tononi
  Nature Neuroscience 11 200 - 208
  (20 January 2008); doi:10.1038/nn2035

  Abstract

• Cytoplasmic BK_Ca channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons

  T. J. Bell, K. Y. Miyashiro, J.-Y. Sul, R. McCullough, P. T. Buckley, J. Jochems, D. F. Meaney, P. Haydon, C. Cantor, T. D. Parsons & J. Eberwine
  Proceedings of the National Academy of Sciences 105
  (12 February 2008); doi:10.1073/pnas.0711796105

  Abstract

• The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of Ca_V1.2 L-type calcium channels

  C. F. Barrett & R. W. Tsien
  Proceedings of the National Academy of Sciences 105
  (12 February 2008); doi:10.1073/pnas.0710501105

  Abstract

• Bcl-x_L induces Drp1-dependent synapse formation in cultured hippocampal neurons

  H. Li, Y. Chen, A. F. Jones, R. H. Sanger, L. P. Collis, R. Flannery, E. C. McNay, T. Yu, R. Schwarzenbacher, B. Bossy, E. Bossy-Wetzel, M. V. L. Bennett, M. Pypaert, J. A. Hickman, P. J. S. Smith, J. M. Hardwick & E. A. Jonas
  Proceedings of the National Academy of Sciences 105
  (12 February 2008); doi:10.1073/pnas.0711647105

  Abstract

• Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

  A. Y. Hung, K. Futai, C. Sala, J. G. Valtschanoff, J. Ryu, M. A. Woodworth, F. L. Kidd, C. C. Sung, T. Miyakawa, M. F. Bear, R. J. Weinberg & M. Sheng
  Journal of Neuroscience 28
  (13 February 2008); doi:10.1523/JNEUROSCI.3032-07.2008

  Abstract

• pH-Dependent Inhibition of Kainate Receptors by Zinc

  D. D. Mott, M. Benveniste & R. J. Dingledine
  Journal of Neuroscience 28
  (13 February 2008); doi:10.1523/JNEUROSCI.3567-07.2008

  Abstract

• Role of Protein Phosphatase 2A in Regulating the Visual Signaling in Drosophila

  N. Wang, H.-T. Leung, W. L. Pak, Y. T. Carl, B. E. Wadzinski & B.-H. Shieh
  Journal of Neuroscience 28
  (6 February 2008); doi:10.1523/JNEUROSCI.5134-07.2008

  Abstract

• Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells

  J.-W. Wang, D. J. David, J. E. Monckton, F. Battaglia & R. Hen
  Journal of Neuroscience 28
  (6 February 2008); doi:10.1523/JNEUROSCI.3632-07.2008

  Abstract

• Adenosine is crucial for deep brain stimulation–mediated attenuation of tremor

  Lane Bekar, Witold Libionka, Guo-Feng Tian, Qiwu Xu, Arnulfo Torres, Xiaohai Wang, Ditte Lovatt, Erika Williams, Takahiro Takano, Jurgen Schnermann, Robert Bakos & Maiken Nedergaard
  Nature Medicine 14 75 - 80
  (23 December 2007); doi:10.1038/nm1693

  Abstract

• Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

  R Seal, O Akil, E Yi, C Weber, L Grant, J Yoo, A Clause, K Kandler, J Noebels & E Glowatzki
  Neuron 57
  (24 January 2008); doi:10.1016/j.neuron.2007.11.032

  Abstract

• Cannabinoids Desensitize Capsaicin and Mustard Oil Responses in Sensory Neurons via TRPA1 Activation

  A. N. Akopian, N. B. Ruparel, A. Patwardhan & K. M. Hargreaves
  Journal of Neuroscience 28
  (30 January 2008); doi:10.1523/JNEUROSCI.1565-06.2008

  Abstract

• Transgenic Inhibition of Synaptic Transmission Reveals Role of CA3 Output in Hippocampal Learning

  T. Nakashiba, J. Z. Young, T. J. McHugh, D. L. Buhl & S. Tonegawa
  Science
  (24 January 2008); doi:10.1126/science.1151120

  Abstract

• Reversal of pathological pain through specific spinal GABA_A receptor subtypes

  Julia Knabl, Robert Witschi, Katharina Hösl, Heiko Reinold, Ulrike B. Zeilhofer, Seifollah Ahmadi, Johannes Brockhaus, Marina Sergejeva, Andreas Hess, Kay Brune, Jean-Marc Fritschy, Uwe Rudolph, Hanns Möhler & Hanns Ulrich Zeilhofer
  Nature 451 330 - 334
  doi:10.1038/nature06493

  Abstract

• Activin tunes GABAergic neurotransmission and modulates anxiety-like behavior

  F Zheng, H Adelsberger, M R Müller, J-M Fritschy, S Werner & C Alzheimer
  Molecular Psychiatry
  (8 January 2008); doi:10.1038/sj.mp.4002131

  Abstract

• A thermosensory pathway that controls body temperature

  Kazuhiro Nakamura & Shaun F Morrison
  Nature Neuroscience 11 62 - 71
  (16 December 2007); doi:10.1038/nn2027

  Abstract

• Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice

  Daniel Huber, Leopoldo Petreanu, Nima Ghitani, Sachin Ranade, Tomá Hromádka, Zach Mainen & Karel Svoboda
  Nature 451 61 - 64
  doi:10.1038/nature06445

  Abstract

• Behavioural report of single neuron stimulation in somatosensory cortex

  Arthur R. Houweling & Michael Brecht
  Nature 451 65 - 68
  doi:10.1038/nature06447

  Abstract

• Adenosine A_2A Receptors Are Essential for Long-Term Potentiation of NMDA-EPSCs at Hippocampal Mossy Fiber Synapses

  N Rebola et al.
  Neuron 57
  (10 January 2008); doi:10.1016/j.neuron.2007.11.023

  Abstract

• Suppression of Neurodegeneration and Increased Neurotransmission Caused by Expanded Full-Length Huntingtin Accumulating in the Cytoplasm

  E Romero et al.
  Neuron 57
  (10 January 2008); doi:10.1016/j.neuron.2007.11.025

  Abstract

• High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT_3AB receptor

  K. Krzywkowski, P. A. Davies, P. L. Feinberg-Zadek, H. Brauner-Osborne & A. A. Jensen
  Proceedings of the National Academy of Sciences 105
  (9 January 2008); doi:10.1073/pnas.0708454105

  Abstract

• Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability

  S. Jacobs, E. Ruusuvuori, S. T. Sipilä, A. Haapanen, H. H. Damkier, I. Kurth, M. Hentschke, M. Schweizer, Y. Rudhard, L. M. Laatikainen, J. Tyynelä, J. Praetorius, J. Voipio & C. A. Hübner
  Proceedings of the National Academy of Sciences 105
  (8 January 2008); doi:10.1073/pnas.0705487105

  Abstract

• Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: Role of corticosterone-mediated apical dendritic atrophy

  R.-J. Liu & G. K. Aghajanian
  Proceedings of the National Academy of Sciences 105
  (8 January 2008); doi:10.1073/pnas.0706679105

  Abstract

• Activity-Dependent Suppression of Miniature Neurotransmission through the Regulation of DNA Methylation

  E. D. Nelson, E. T. Kavalali & L. M. Monteggia
  Journal of Neuroscience 28
  (9 January 2008); doi:10.1523/JNEUROSCI.3796-07.2008

  Abstract

• Constitutively Active TRPC3 Channels Regulate Basal Ganglia Output Neurons

  F.-W. Zhou, S. G. Matta & F.-M. Zhou
  Journal of Neuroscience 28
  (9 January 2008); doi:10.1523/JNEUROSCI.3978-07.2008

  Abstract

• Locally dynamic synaptic learning rules in pyramidal neuron dendrites

  Christopher D. Harvey & Karel Svoboda
  Nature 450 1195 - 1200
  (20 December 2007); doi:10.1038/nature06416

  Abstract

• Correction of Fragile X Syndrome in Mice

  G Dolen et al.
  Neuron 56 955 - 962
  (20 December 2007); doi:10.1016/j.neuron.2007.12.001

  Abstract

• Ongoing in Vivo Experience Triggers Synaptic Metaplasticity in the Neocortex

  R. L. Clem, T. Celikel & A. L. Barth
  Science 319
  (4 January 2008); doi:10.1126/science.1143808

  Abstract

• Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves

  R. D. Shah & M. C. Crair
  Journal of Neuroscience 28
  (2 January 2008); doi:10.1523/JNEUROSCI.4276-07.2008

  Abstract

• Vasopressin Increases Locomotion through a V1a Receptor in Orexin/Hypocretin Neurons: Implications for Water Homeostasis

  T. Tsunematsu, L.-Y. Fu, A. Yamanaka, K. Ichiki, A. Tanoue, T. Sakurai & A. N. van den Pol
  Journal of Neuroscience 28
  (2 January 2008); doi:10.1523/JNEUROSCI.3490-07.2008

  Abstract

• KCC2 Interacts with the Dendritic Cytoskeleton to Promote Spine Development

  H Li et al.
  Neuron 56
  (20 December 2007); doi:10.1016/j.neuron.2007.10.039

  Abstract

• Long-Term Potentiation in Rat Hippocampal Neurons Is Accompanied by Spatially Widespread Changes in Intrinsic Oscillatory Dynamics and Excitability

  R Narayanan et al.
  Neuron 56
  (20 December 2007); doi:10.1016/j.neuron.2007.10.033

  Abstract