Genetics

• Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

  T. Walsh, J. M. McClellan, S. E. McCarthy, A. M. Addington, S. B. Pierce, G. M. Cooper, A. S. Nord, M. Kusenda, D. Malhotra, A. Bhandari, S. M. Stray, C. F. Rippey, P. Roccanova, V. Makarov, B. Lakshmi, R. L. Findling, L. Sikich, T. Stromberg, B. Merriman, N. Gogtay, P. Butler, K. Eckstrand, L. Noory, P. Gochman, R. Long, Z. Chen, S. Davis, C. Baker, E. E. Eichler, P. S. Meltzer, S. F. Nelson, A. B. Singleton, M. K. Lee, J. L. Rapoport, M.-C. King & J. Sebat
  Science
  (27 March 2008); doi:10.1126/science.1155174

  Abstract

• A Novel Embryonic Nestin-Expressing Radial Glia-Like Progenitor Gives Rise to Zonally Restricted Olfactory and Vomeronasal Neurons

  B. Murdoch & A. J. Roskams
  Journal of Neuroscience 28
  (16 April 2008); doi:10.1523/JNEUROSCI.5566-07.2008

  Abstract

• Sex-Specific Differences in Expression of Histone Demethylases Utx and Uty in Mouse Brain and Neurons

  J. Xu, X. Deng, R. Watkins & C. M. Disteche
  Journal of Neuroscience 28
  (23 April 2008); doi:10.1523/JNEUROSCI.5382-07.2008

  Abstract

• Genetic variation in human NPY expression affects stress response and emotion

  Zhifeng Zhou, Guanshan Zhu, Ahmad R. Hariri, Mary-Anne Enoch, David Scott, Rajita Sinha, Matti Virkkunen, Deborah C. Mash, Robert H. Lipsky, Xian-Zhang Hu, Colin A. Hodgkinson, Ke Xu, Beata Buzas, Qiaoping Yuan, Pei-Hong Shen, Robert E. Ferrell, Stephen B. Manuck, Sarah M. Brown, Richard L. Hauger, Christian S. Stohler, Jon-Kar Zubieta & David Goldman
  Nature 452 997 - 1001
  (2 April 2008); doi:10.1038/nature06858

  Abstract

• Brain Chromatin Remodeling: A Novel Mechanism of Alcoholism

  S. C. Pandey, R. Ugale, H. Zhang, L. Tang & A. Prakash
  Journal of Neuroscience 28
  (2 April 2008); doi:10.1523/JNEUROSCI.5731-07.2008

  Abstract

• Genetic control of neuronal activity in mice conditionally expressing TRPV1

  Benjamin R Arenkiel, Marguerita E Klein, Ian G Davison, Lawrence C Katz & Michael D Ehlers
  Nature Methods
  (9 March 2008); doi:10.1038/nmeth.1190

  Abstract

• Postmitotic Specification of Drosophila Insulinergic Neurons from Pioneer Neurons

  Irene Miguel-aliaga, Stefan Thor & Alex P. Gould
  PLoS Biology 6
  (1 January 2008); doi:10.1371/journal.pbio.0060058

  Abstract

• C. elegans Model Identifies Genetic Modifiers of &alpa;-Synuclein Inclusion Formation During Aging

  Tjakko J. van Ham, Karen L. Thijssen, Rainer Breitling, Robert M. W. Hofstra, Ronald H. A. Plasterk, Ellen A. A. Nollen & Stuart K. Kim
  PLoS Genetics 4
  (21 March 2008); doi:10.1371/journal.pgen.1000027

  Abstract

• SIRT1 Inhibition Alleviates Gene Silencing in Fragile X Mental Retardation Syndrome

  Rea Biacsi, Daman Kumari, Karen Usdin & Harry Orr
  PLoS Genetics 4
  (14 March 2008); doi:10.1371/journal.pgen.1000017

  Abstract

• A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors

  F. Qiu, H. Jiang & M. Xiang
  Journal of Neuroscience 28
  (26 March 2008); doi:10.1523/JNEUROSCI.0043-08.2008

  Abstract

• Redefining the serotonergic system by genetic lineage

  Patricia Jensen, Anna F Farago, Rajeshwar B Awatramani, Michael M Scott, Evan S Deneris & Susan M Dymecki
  Nature Neuroscience 11 417 - 419
  (16 March 2008); doi:10.1038/nn2050

  Abstract

• TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

  J. Sreedharan, I. P. Blair, V. B. Tripathi, X. Hu, C. Vance, B. Rogelj, S. Ackerley, J. C. Durnall, K. L. Williams, E. Buratti, F. Baralle, J. de Belleroche, J. D. Mitchell, P. N. Leigh, A. Al-Chalabi, C. C. Miller, G. Nicholson & C. E. Shaw
  Science
  (28 February 2008); doi:10.1126/science.1154584

  Abstract

• The Drosophila pheromone cVA activates a sexually dimorphic neural circuit

  Sandeep Robert Datta, Maria Luisa Vasconcelos, Vanessa Ruta, Sean Luo, Allan Wong, Ebru Demir, Jorge Flores, Karen Balonze, Barry J. Dickson & Richard Axel
  Nature
  (27 February 2008); doi:10.1038/nature06808

  Abstract

• Hybrid Neurons in a MicroRNA Mutant Are Putative Evolutionary Intermediates in Insect CO₂ Sensory Systems

  P. Cayirlioglu, I. G. Kadow, X. Zhan, K. Okamura, G. S. B. Suh, D. Gunning, E. C. Lai & S. L. Zipursky
  Science 319
  (29 February 2008); doi:10.1126/science.1149483

  Abstract

• Alleviation of A-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model

  D Takeuchi, N Sato, M Shimamura, H Kurinami, S Takeda, M Shinohara, S Suzuki, M Kojima, T Ogihara & R Morishita
  Gene Therapy
  (21 February 2008); doi:10.1038/sj.gt.3303094

  Abstract

• A common polymorphism in serotonin receptor 1B mRNA moderates regulation by miR-96 and associates with aggressive human behaviors

  K P Jensen, J Covault, T S Conner, H Tennen, H R Kranzler & H M Furneaux
  Molecular Psychiatry
  (19 February 2008); doi:10.1038/mp.2008.15

  Abstract

• Spine-Type-Specific Recruitment of Newly Synthesized AMPA Receptors with Learning

  N. Matsuo, L. Reijmers & M. Mayford
  Science 319
  (22 February 2008); doi:10.1126/science.1149967

  Abstract

• Uncovering trends in gene naming

  Michael R Seringhaus, Philip D Cayting & Mark B Gerstein
  Genome Biology 9
  (31 January 2008); doi:10.1186/gb-2008-9-1-401

  Abstract

• Cytoplasmic BK_Ca channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons

  T. J. Bell, K. Y. Miyashiro, J.-Y. Sul, R. McCullough, P. T. Buckley, J. Jochems, D. F. Meaney, P. Haydon, C. Cantor, T. D. Parsons & J. Eberwine
  Proceedings of the National Academy of Sciences 105
  (12 February 2008); doi:10.1073/pnas.0711796105

  Abstract

• Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression

  M Uhr, A Tontsch, C Namendorf, S Ripke, S Lucae, M Ising, T Dose, M Ebinger, M Rosenhagen & M Kohli
  Neuron 57
  (24 January 2008); doi:10.1016/j.neuron.2007.11.017

  Abstract

• Genes and (Common) Pathways Underlying Drug Addiction

  Chuan-Yun Li, Xizeng Mao & Liping Wei
  PLoS Computational Biology 4
  (4 January 2008); doi:10.1371/journal.pcbi.0040002

  Abstract

• Immediate-Early Gene Expression at Rest Recapitulates Recent Experience

  D. F. Marrone, M. J. Schaner, B. L. McNaughton, P. F. Worley & C. A. Barnes
  Journal of Neuroscience 28
  (30 January 2008); doi:10.1523/JNEUROSCI.4235-07.2008

  Abstract

• Members of the miRNA-200 Family Regulate Olfactory Neurogenesis

  P Choi et al.
  Neuron 57
  (10 January 2008); doi:10.1016/j.neuron.2007.11.018

  Abstract

• Activity-Dependent Suppression of Miniature Neurotransmission through the Regulation of DNA Methylation

  E. D. Nelson, E. T. Kavalali & L. M. Monteggia
  Journal of Neuroscience 28
  (9 January 2008); doi:10.1523/JNEUROSCI.3796-07.2008

  Abstract

• Association between Microdeletion and Microduplication at 16p11.2 and Autism

  L. A. Weiss, Y. Shen, J. M. Korn, D. E. Arking, D. T. Miller, R. Fossdal, E. Saemundsen, H. Stefansson, M. A.R. Ferreira, T. Green, O. S. Platt, D. M. Ruderfer, C. A. Walsh, D. Altshuler, A. Chakravarti, R. E. Tanzi, K. Stefansson, S. L. Santangelo, J. F. Gusella, P. Sklar, B.-L. Wu & M. J. Daly
  New England Journal of Medicine
  (9 January 2008); doi:10.1056/nejmoa075974

  Abstract

• Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory

  Y. Zhang, A. Bertolino, L. Fazio, G. Blasi, A. Rampino, R. Romano, M.-L. T. Lee, T. Xiao, A. Papp, D. Wang & W. Sadée
  Proceedings of the National Academy of Sciences 104
  (18 December 2007); doi:10.1073/pnas.0707106104

  Abstract