Genomics

• Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

  T. Walsh, J. M. McClellan, S. E. McCarthy, A. M. Addington, S. B. Pierce, G. M. Cooper, A. S. Nord, M. Kusenda, D. Malhotra, A. Bhandari, S. M. Stray, C. F. Rippey, P. Roccanova, V. Makarov, B. Lakshmi, R. L. Findling, L. Sikich, T. Stromberg, B. Merriman, N. Gogtay, P. Butler, K. Eckstrand, L. Noory, P. Gochman, R. Long, Z. Chen, S. Davis, C. Baker, E. E. Eichler, P. S. Meltzer, S. F. Nelson, A. B. Singleton, M. K. Lee, J. L. Rapoport, M.-C. King & J. Sebat
  Science
  (27 March 2008); doi:10.1126/science.1155174

  Abstract

• A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures

  Andrew J Sharp, Heather C Mefford, Kelly Li, Carl Baker, Cindy Skinner, Roger E Stevenson, Richard J Schroer, Francesca Novara, Manuela De gregori, Roberto Ciccone, Adam Broomer, Iris Casuga, Yu Wang, Chunlin Xiao, Catalin Barbacioru, Giorgio Gimelli, Bernardo Dalla Bernardina, Claudia Torniero, Roberto Giorda, Regina Regan, Victoria Murday, Sahar Mansour, Marco Fichera, Lucia Castiglia, Pinella Failla, Mario Ventura, Zhaoshi Jiang, Gregory M Cooper, Samantha J L Knight, Corrado Romano, Orsetta Zuffardi, Caifu Chen, Charles E Schwartz & Evan E Eichler
  Nature Genetics 40 322 - 328
  (17 February 2008); doi:10.1038/ng.93

  Abstract

• Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

  W. S. Liang, E. M. Reiman, J. Valla, T. Dunckley, T. G. Beach, A. Grover, T. L. Niedzielko, L. E. Schneider, D. Mastroeni, R. Caselli, W. Kukull, J. C. Morris, C. M. Hulette, D. Schmechel, J. Rogers & D. A. Stephan
  Proceedings of the National Academy of Sciences 105
  (18 March 2008); doi:10.1073/pnas.0709259105

  Abstract

• A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors

  F. Qiu, H. Jiang & M. Xiang
  Journal of Neuroscience 28
  (26 March 2008); doi:10.1523/JNEUROSCI.0043-08.2008

  Abstract

• TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

  J. Sreedharan, I. P. Blair, V. B. Tripathi, X. Hu, C. Vance, B. Rogelj, S. Ackerley, J. C. Durnall, K. L. Williams, E. Buratti, F. Baralle, J. de Belleroche, J. D. Mitchell, P. N. Leigh, A. Al-Chalabi, C. C. Miller, G. Nicholson & C. E. Shaw
  Science
  (28 February 2008); doi:10.1126/science.1154584

  Abstract

• Quantitative methods for genome-scale analysis of in situ hybridization and correlation with microarray data

  Chang-Kyu Lee, Susan M Sunkin, Chihchau Kuan, Carol L Thompson, Sayan Pathak, Lydia Ng, Chris Lau, Shana Fischer, Marty Mortrud, Cliff Slaughterbeck, Allan Jones, Ed Lein & Michael Hawrylycz
  Genome Biology 9
  (30 January 2008); doi:10.1186/gb-2008-9-1-r23

  Abstract

• A Systems Level Analysis of Transcriptional Changes in Alzheimer's Disease and Normal Aging

  J. A. Miller, M. C. Oldham & D. H. Geschwind
  Journal of Neuroscience 28
  (6 February 2008); doi:10.1523/JNEUROSCI.4098-07.2008

  Abstract

• A role for adult TLX-positive neural stem cells in learning and behaviour

  Chun-Li Zhang, Yuhua Zou, Weimin He, Fred H. Gage & Ronald M. Evans
  Nature 451 1004 - 1007
  (30 January 2008); doi:10.1038/nature06562

  Abstract

• Genes and (Common) Pathways Underlying Drug Addiction

  Chuan-Yun Li, Xizeng Mao & Liping Wei
  PLoS Computational Biology 4
  (4 January 2008); doi:10.1371/journal.pcbi.0040002

  Abstract

• Specific expression of long noncoding RNAs in the mouse brain

  T. R. Mercer, M. E. Dinger, S. M. Sunkin, M. F. Mehler & J. S. Mattick
  Proceedings of the National Academy of Sciences 105
  (9 January 2008); doi:10.1073/pnas.0706729105

  Abstract

• Association between Microdeletion and Microduplication at 16p11.2 and Autism

  L. A. Weiss, Y. Shen, J. M. Korn, D. E. Arking, D. T. Miller, R. Fossdal, E. Saemundsen, H. Stefansson, M. A.R. Ferreira, T. Green, O. S. Platt, D. M. Ruderfer, C. A. Walsh, D. Altshuler, A. Chakravarti, R. E. Tanzi, K. Stefansson, S. L. Santangelo, J. F. Gusella, P. Sklar, B.-L. Wu & M. J. Daly
  New England Journal of Medicine
  (9 January 2008); doi:10.1056/nejmoa075974

  Abstract

• A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

  J. D. Cahoy, B. Emery, A. Kaushal, L. C. Foo, J. L. Zamanian, K. S. Christopherson, Y. Xing, J. L. Lubischer, P. A. Krieg, S. A. Krupenko, W. J. Thompson & B. A. Barres
  Journal of Neuroscience 28
  (2 January 2008); doi:10.1523/JNEUROSCI.4178-07.2008

  Abstract